RNA Details
Disease Name
renal interstitial fibrosis
Tissue
kidney
RNA Symbol
mir-4709-3p
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
FISH;RT-qRT-PCR;luciferase assay
Target
LATS2
Pathway
HIPPO SIGNALING PATHWAY
PubMed ID
Title
MicroRNA miR-4709-3p targets Large Tumor Suppressor Kinase 2 (LATS2) and induces obstructive renal fibrosis through Hippo signaling
Year
2021
Function
"Aberrant miR-4709-3p expression plays an essential function in the renal fibrosis progression, and miR-4709-3p overexpression could advance obstructive renal fibrosis via LATS2 targeting in Hippo signaling pathway."